کاربردهای زیستی پوشش‌های نانوساختار بر پایه کربن

نوع مقاله : مقاله مروری

نویسندگان

1 استادیار،گروه نانوفناوری رنگ- موسسه پژوهشی علوم و فناوری رنگ و پوشش

2 شرکت اطلس پوشش محافظ

چکیده

تعمیر و جایگزینی بافت‌ها و اندام‌های بیمار و آسیب دیده انسانی با استفاده از قطعات روز به روز در حال افزایش است. طول عمر و زیست‌سازگاری بالا، دو عامل اصلی در فرآیند طراحی و ساخت قطعات مورد استفاده در پزشکی (نظیر ایمپلنت‌های زیستی)، محسوب می‌شوند. یکی از بزرگ‌ترین مشکلات قطعات مورد استفاده در پزشکی سایش می‌باشد. به‌منظور بهبود مقاومت سایشی، می‌توان از پوشش‌های محافظتی استفاده نمود. از سوی دیگر، بیشتر قطعات زیستی فلزی بوده و احتمال آزاد شدن یون‌های فلزی خطرناک از سطح آن‌ها و ورود آن‌ها به بدن وجود دارد که این پوشش محافظ می‌تواند به عنوان سدی در برابر آزاد شدن و نفوذ یون‌ها به بافت بدن عمل نمایند. نتایج تحقیقات متعدد نشان داده است که پوشش‌های نانوساختار پوشش‌های الماس‌گون کربنی (Diamond-Like Carbon (DLC)) توانایی ایجاد این خواص را بر سطح قطعات زیستی دارند. پوشش‌های الماس‌گون کربنی به‌دلیل وجود نواحی گرافیتی بر سطح خود، ضریب اصطکاک بسیار پائینی داشته و مقاومت سایشی پوشش‌ها را بهبود می‌بخشند. از طرفی با کنترل شرایط اعمال آن‌ها، می‌توان پوشش‌هایی با خواص مکانیکی خوب و سختی بالا (حدود الماس) را به‌دست آورد که خواص تریبولوژی سطح را به میزان قابل ملاحظه‌ای بهبود خواهند بخشید. این پوشش‌ها به روش‌های متعددی نظیر لایه نشانی فیزیکی از فاز بخار (PVD) و لایه نشانی شیمیایی از فاز بخار (CVD) تهیه می‌شوند و با اضافه کردن عناصری نظیر نیتروژن، مس و نقره می‌توان خواص ویژه‌ای را بر سطح آن‌ها بوجود آورد. مقاله حاضر در برگیرنده‌ مطالعات انجام شده در حوزه‌ استفاده از پوشش‌های نانوساختار الماس‌گون کربنی (DLC) در کاربردهای پزشکی نظیر ارتوپدی، سامانه قلبی عروقی، چشم پزشکی (لنزهای تماسی) و دندانپزشکی می‌باشد.

کلیدواژه‌ها

موضوعات

عنوان مقاله [English]

Biomedical Applications of Nanostructured Carbon-Based Coatings

نویسندگان [English]

  • Sara Khamseh 1
  • Eiman Alibakhshi 2
1 Department of Nanomaterials and Nanocoatings, Institute for Colour Science and Technology
2 Atlas Protecting Coating Company
چکیده [English]

The repair and replacement of diseased tissues and injured organs of humans is increasing day by day. Long lifetime and high biocompatibility are two main factors in the process of designing and manufacturing components used in medicine (such as biological implants). Wear is one of the biggest problems with the parts used in medicine. The protective coatings can be used to improve the wear resistance. On the other hand, most of the biodegradable parts are metallic, and there is a possibility that dangerous metal ions will be released from their surface and enter the body. Protective coatings can be used as a barrier against the release and penetration of ions affect the body's tissues. Numerous studies have shown that nanostructured diamond-like carbon coatings (DLC) have the ability to create these properties on the surface of biological components. These coatings are produced with several methods, such as the physical vapor barrier layer (PVD) and the chemical vapor barrier chemical layer (CVD), and by doping elements of nitrogen, copper and silver, unique properties can be created on their surface. The present paper includes studies in the field of using diamond carbon nanostructured coatings such as (DLC) in medical applications such as orthopedics, cardiovascular system, ophthalmology and dentistry.
 

کلیدواژه‌ها [English]

  • Diamond-like carbon coatings
  • Biomedical
  • Biocompatibility
  • Synthesis methods

مراجع

  1. Y. Liu, A. Erdemir, E.I. Meletis, "A study of the wear mechanism of diamond-like carbon films", Surf. Coat. Technol. 82, 48-56, 1996.
  2. A.A. Voevodin, M.S. Donley, J.S. Zabinski, "Pulsed laser deposition of diamond-like carbon wear protective coatings: a review", Surf. Coat. Technol. 92, 42-49, 1997.
  3. Q. Wei, J. Sankos, J. Narayan, " Structure and properties of novel functional diamond-like carbon coatings produced by laser ablation", Surf. Coat. Technol. 146–147, 250-257, 2001.
  4. S. Xu, B. K. Tay, H. S. Tan, L. Zhong, S. R. F. Silva,W. I. Milne, "Properties of carbon ion deposited tetrahedral amorphous carbon films as a function of ion energy", J. Appl. Phys. 79, 7234-7240, 1996.
  5. P. Lu, Y.K. Chou, "Analysis of acoustic emission signal evolution for monitoring diamond-coated tool delamination wear in machining", Machining and machine-tools Research and Development Woodhead Publishing Reviews: Mechanical Engineering Series. 1-28, 2013.
  6. M. Chandran, "Synthesis, Characterization, and applications of diamond films", Carbon-Based Nanofillers and Their Rubber Nanocomposites, Chapter Six, Carbon Nano-Objects, 183-224, 2019.
  7. R. J. Narayan, R. D. Boehm, A. V. Sumant, " Introduction to medical applications of diamond particles and surfaces, Diamond-Based Materials for Biomedical Applications, Woodhead Publishing Series in Biomaterials", 3-24, 2011.
  8. W. Ahmed, H. Sein, M. Jackson, C. Rego, I. U. Hassan, K. Subramani, J. Yazdani, "Surface Engineering of Dental Tools with Diamond for Improved Life and Performance", Chapter 15, Emerging Nanotechnologies in Dentistry Processes, Materials and Applications Micro and Nano Technologies, 239-272, 2012.
  9. S. Anders, A. Anders, I. E. Brown, B. Wei, J. W. Ager, K. M. Yu, "Effect of vacuum arc deposition parameters on the properties of amorphous carbon thin films", Surf. Coat. Technol. 68– 69, 388-393, 1994.
  10. X. L. Peng, Z. H. Barber, T. W. Clyne, "Surface roughness of diamond-like carbon films prepared using various techniques", Surf. Coat. Technol. 138, 23-32, 2001.
  11. S. Khamseh, E. Alibakhshi, B. Ramezanzadeh, M. Ganjaee Sari, A. Kazemi Nezhad, "Developing a Graphite like Carbon:Niobium thin film on GTD-450 stainless steel substrate", Appl. Surf. SCi. 511, 145613. 2020.
  12. P. Brouki Milan, S. Khamseh, P. Zarrintaj, B. Ramezanzadeh, M. Badawi, S. Morisset, H. Vahabi, M. R. Saeb, M. Mozafari, "Copper-enriched diamond-like carbon coatings promote regeneration at the bone–implant interface", Heliyon. 6, Doi: 10.1016/j.heliyon.2020.e03798, 2020.
  13. M. R. Derakhshandeh, M. J. Eshraghi, M. Javaheri, S. Khamseh, M. Ganjaee Sari, P. Zarrintaj, M. R. Saeb, Masoud Mozafari, "Diamond-like carbon-deposited films: a new class of biocorrosion protective coatings", Surf. Innov. 6, 266–276, 2018.
  14. M. R. Derakhshandeh, M. J. Eshraghi, M. Javaheri, S. Khamseh, M. Ganjaee Sari, P. Zarrintaj, M. R. Saeb, Masoud Mozafari, "Diamond-like carbon thin films prepared by pulsed-DC PE-CVD for biomedical applications", Surf. Innov. 6, 167–175, 2018.
  15. S. Khamseh, E. Alibakhshi, M. Mahdavian, M. R. Saeb, H. Vahabi, N. Kokanyan, P. Laheurte, "Magnetron-sputtered copper/diamond-like carbon composite thin films with super anti-corrosion properties", Surf. Coat. Technol. 333, 148-157, 2018.
  16. K. A. H. Al Mahmud, M. A. Kalam, H.H. Masjuki, H. M. Mobarak, N. W. M. ZUlkifli, "An updated overview of diamond-like carbon coating in tribology", Crit. Rev. Solid State. 40, 90-118, 2015.
  17. A. Modabber Asl, P. Kameli, M. Ranjbar, H. Salamati, M. Jannesari, "Correlations between microstructure and hydrophobicity properties of pulsed laser deposited diamond-like carbon films", Superlattice Microst. 81, 64-79, 2015.
  18. K. Honglertkongsakul, P.W. May, B. Paosawatyanyong, "Electrical and optical properties of diamond-like carbon films deposited by pulsed laser ablation", Diamond Relat. Mater.19, 999-1002, 2010.
  19. B. Y. Oh, Y. S. Park, "Characteristics of diamond-like carbon films fabricated by using a filtered vacuum arc system for dye-sensitized solar cells, J. Korean. Phys. Soc. 75, 586–590, 2019.
  20. F.Z. Cui, X.L. Qing, D.J. Li, J. Zhao, "Biomedical investigations on CNx coating", Surf. Coat. Technol. 200, 1009-1013, 2005.
  21. E. Broitman,W. Macdonald, N. Hellgren, G. Radnoczi, Z. Czigany, A. Wennerberg, M. Jacobsson, L. Hultman, "Carbon nitride films on orthopedic substrates", Diamond Relat. Mater. 9, 1984-1991, 2000.
  22. A. Erdemir, J.B. Nilufer, O.C. Eryilmaz, G.R. Fenske, "Friction and wear performance of diamond-like carbon films grown in various source gas plasmas", Surf. Coat. Technol. 120– 121, 589-593, 1999.
  23. Y. Iwamoto, K.Takenami, R. Takamura, M. Inoue, Y. Hirara, H. Akasaka, N. Ohtake, "Preparation of DLC films on inner surfaces of metal tubes by nanopulse plasma CVD", Surf. Coat. Technol. 380, 125062, 2019.
  24. Y. Liu, E.I. Meletis, "Evidence of graphitization of diamond-like carbon films during sliding wear", J. Mater. Sci. 32, 3491-3495, 1997.
  25. P. Ashtijoo, S. Bhattacherjee, R. Sutarto, Y. Hu, Q. Yang, "Fabrication and characterization of adherent diamond-like carbon based thin films on polyethylene terephthalate by end hall ion beamdeposition", Surf. Coat. Technol. 308, 90–97, 2016.
  26. F. F. He, W. Q. Bai, L. L. Li, X. L. Wang, Y. J. Xie, G. Jin, J. P. Tu, "Enhancement of adhesion by a transition layer: Deposition of a-C filmon ultrahigh molecular weight polyethylene (UHMWPE) bymagnetron sputtering", Appl. Surf. Sci. 364, 280–287, 2016.

27. N. Harrasser, S. Jüssen, A. Obermeir, R. Kmeth, B. Stritzker, H. Gollwitzer, R. Burgkart, "Antibacterial potency of different deposition methods of silver and copper containing diamond-like carbon coated polyethylene", Biomater. Res. 17, 20, 2016.

28. V. Saikko, T. Altroos, O. Calonius, J. Keranen, "Wear simulation of total hip prostheses with polyethylene against CoCr, alumina and diamond-like carbon", Biomater. 22, 1507-1514, 2001.

29  D. Sheeja, B.K. Tay, S.P. Lau, L.N. Nung, "Tribological characterisation of diamond-like carbon coatings on Co–Cr–Mo alloy for orthopaedic applications", Surf. Coat. Technol. 146–147, 410-416, 2001.

30 D. Sheeja, B.K. Tay, L.N. Nung, "Tribological characterization of surface modified UHMWPE against DLC-coated Co–Cr–Mo", Surf. Coat. Technol. 190, 231-237, 2005.

31  T. Xu, L. Pruitt, "Diamond-like carbon coatings for orthopaedic applications: an evaluation of tribological performance", Mater. Med. 10, 83-90, 1999.

32  J.I. On˜ ate, M. Comin, I. Braceras, A. Garcia, J.I. Alava,. "Wear reduction effect on ultra-high-molecular-weight polyethylene by application of hard coatings and ion implantation on cobalt chromium alloy, as measured in a knee wear simulation machine", Suf. Coat. Technol. 142–144, 1056-1062, 2001.

33   R. Lappalainen, A. Anttila, H. Heinonen, "Diamond coated total hip replacements", Clin. Orthop. Relat. Res. 352, 118-127, 1998.

34   J. P. Hirvonen, R. Lappalainen, J. Koskinen, A. Anttila, T.R.Jervis, M. Trakula, "Tribological characteristics of diamond-like films deposited with an are-discharge method", J. Mater. Res. 5(1990), 2524.

35  L. A. Thompson, F. C. Law, N. Rushton, J. Franks, "Biocompatibility of diamond-like carbon coating", Biomater. 12, 37-40, 1991.

36 M. Allen, F. Law, N. Rushton, "The effects of diamond-like carbon coatings on macrophages, fibroblasts and osteoblast-like cells in vitro", Clin. Mater. 17, 1-10, 1994.

37  R. S. Butter, A. H. Lettington, "Diamond-like carbon for biomedical applications", J. Chem. Vapor Depos. 3, 182-192, 1995.

38  M. Allen, B. Myer, N. Rushton, "In vitro and in vivo investigations into the biocompatibility of diamond‐like carbon (DLC) coatings for orthopedic applications", J. Biomed. Mater. Res. 58, 319-328, 2001.

39  D. Liu, H. Ma, Y. Liang, L. zheng, "In vitro and in vivo biocompatibility and bio-tribological properties of the calcium/amorphous-C composite films for bone tissue engineering application", Colloids Surf. B. Biointerfaces. 188, 2020.

40  C. Jongwannasiri,T. Charasseangpaisarn, S. Watanabe, "Preliminary testing for reduction of insertion torqueof orthodontic mini-screw implant using diamond-like carbon films", J. Phys. Conf. Ser. 1380, 012062, 2019.

41     K. Gutensohn, C. Beyrhien, M. Brockmann, J. Bau, P. Keuhnl, 10th Congress on Thrombosis, 24, Porto, May, 2000.

42   A. Alanazi, C. Nojiri, T. Noguchi, T. Kido, Y. Komatsu, K. Hirakuri, A. Funakubo, K. Sakai, "Improved Blood Compatibility of DLC Coated Polymeric Material", Asaio J. 440-443, 2000.

43  V. Elinson, V. V. Sleptsov, A. N. Laymin, A. D. Moussina, "Barrier properties of carbon films deposited on polymer-based devices in aggressive environments", Diamond Relat. Mater. 8, 2103-2109, 1999.

44  J. McLaughlin, B. Meenan, P. Maguire, J. Jamieson, "Properties of diamond like carbon thin film coatings on stainless steel medical guidewires", Diamond Relat. Mater. 5, 486-491, 1991.

45   R.S. Butter, A.H. Lettington, J. Chem. Vapor Depos. 3, 182, 1995.

46   I. Efeoglu, O. Baran, G. Urvasızoğlu, A. Keleş, M. Atatol, Y. Totik, Ü. Ertaş, "The Structural Properties of Ta Doped DLC Coatings for the dental applications using HiPIMS", Solid State Sci. Technol. 27,68-74, 2019.

 

مطالعات در دنیای رنگ
دوره 10، شماره 2
شهریور 1399
صفحه 29-40

فایل ها

سابقه مقاله

  • تاریخ دریافت: 10 خرداد 1399
  • تاریخ بازنگری: 19 مرداد 1399
  • تاریخ پذیرش: 22 مرداد 1399

هم رسانی

ارجاع به این مقاله

آمار